http://www.vighter.com/wp-content/uploads/2012/08/DHB-Memo-120308-Ketamine.pdf

note the intranasal dosage of ketamine. remember its for analgesia objective not sedation.

for sedation, intranasally, I have used the traditional IMI dosing .

Just here the link to that interesting page we mentioned:

http://www.intranasal.net/Home/default.htm

Scroll to the Fentanyl/Ketamine section for details and literature
(note mention of a case from Cliff Reid

I remember reading these references by the US Army from the site (one of them only
partly, when you get to the different scores for the 43rd rifle shooting test morphine-ketamine
it’s tiring).
What really called my attention was the slide-show reference with one slide (nr.5) with perhaps
the two most interesting points:

Quote:
“Optimal (IN) dose is 30-50 mg”
“Absolute bioavailability is 35,5%” (suppose IN vs IV?!)

in the same slide they mention 18 mg as iv analgesic dose (might be, used it already like
that in a few cases with my own made-up calculation of 0,3 mg/kg iv to good effect)
but the the 280 mg/kg iv as anesthetic dose is in my opinion/experience quite more than needed (well, perhaps I’m not taking in account obese soldiers?).

But with IN Ketamine, so far, the very sparse literature has very varying doses for analgesia thresholds, whereas that means we still have to find the optimal dose or reflects a great interindividual difference I’m not sure…

Anyways, so far the IN route stays interesting, I’m looking forward to hear/read more about this great option in the future.

I’d love to hear of your thoughts/opinions and perhaps IN dosing tips!?

Stay safe and as always: take good care of yourselves and others…