PHARM Podcast 78 Ketamine MythBusters Part 4 – A fitting end?

A little bit of this and a little bit of that..

A little bit of this and a little bit of that..


Tonight on the podcast , we bust another ketamine myth. Ketamine and epilepsy. Does it cause seizures? can it be used to manage seizures?

Thanks to a long time colleague of mine Dr Johann Hiesmair who is an Austrian anaesthetist and used to work with RFDS Queensland in Rockhampton. He brought up the question having to deal with a real life case.

TAKE HOME MESSAGES:

  • Ketamine does not cause epilepsy or induce seizures in patients with epilepsy
  • There is one case report in anaesthetic literature of ketamine administration being associated with a seizure in a child
  • There are several case reports of ketamine being used to treat refractory seizures, unresponsive to first and second line antiseizure medications
  • Ketamine has advantages over traditional antiseizure medications with less respiratory depression and hypotension

REFERENCES:

  1. Ketamine and epilepsy
  2. Effects of ketamine on epilepsy
  3. Ketamine induced seizures – a case report
  4. Ketamine successfully terminates malignant status epilepticus
  5. Oral ketamine controlled nonconvulsive status epilepticus in elderly patient
  6. Ketamine may help refractory status epilepticus
  7. Ketamine use in the treatment of refractory status epilepticus
  8. Early ketamine to treat refractory status epilepticus

Now on to the AudioPodcast ( available here and on iTunes)

Right Click and Choose Save-as to Download the Podcast.

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