PHARM Podcast 116 : Droperidol, Ketamine, Surviving Sedation & ECMO with Dr Michael Downes

Hi Folks

On today’s show, we chat to Dr Michael Downes, emergency physician and medical toxicologist at NewCastle , NSW. We cover the DORM studies ( 1st and 2nd ), ketamine sedation in ED for acute agitation, metamphetamine intoxication, ECMO for poisonings and an upcoming international toxicology conference in Perth in December 2015!

Tune in to find out the details!


Show note references:

  1. Leonie Calver; Colin B. Page, MBChB; Michael A. Downes, MBBS; Betty Chan, MBBS, PhD; Frances Kinnear, MBBS; Luke Wheatley, MBBS; David Spain, MBBS; Geoffrey Kennedy Isbister, MD, BS. The Safety and Effectiveness of Droperidol for Sedation of Acute Behavioral Disturbance in the Emergency Department (DORM II study). Ann Emerg Med. 2015;-:1-9
  2. G Isbister et al. Randomized controlled trial of intramuscular droperidol versus midazolam for violence and acute behavioral disturbance: the DORM study. Ann Emerg Med. 2010 Oct;56(4):392-401
  3. E Chan et al. Intravenous Droperidol or Olanzapine as an Adjunct to Midazolam for the Acutely Agitated Patient: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Ann Emerg Med, 2013, 61(1) :72-81
  4. Calver LA1, Stokes B, Isbister GK.Sedation assessment tool to score acute behavioural disturbance in the emergency department.Emerg Med Australas. 2011 Dec;23(6):732-40.
  5. Surviving Sedation guidelines 2015
  6. Toxicology and Poisons Network Australasia
  7. Asia Pacific Association of Medical Toxicology 2015

Register for SMACC please!


  1. Now, onto the PODCAST!



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